Which type forms the lining of very active parts of the body such as the stomach and consists of a single layer of tall, rectangular cells attached to a basement membrane?

• A. Simple cuboidal epithelium
• B. Stratified squamous epithelium
• C. Columnar epithelium
• D. Simple squamous epithelium

Answer: (C)

Columnar epithelium forms the lining of highly active regions like the stomach because it is a single layer of tall, column-shaped cells attached to a basement membrane. This tall, narrow arrangement provides a sturdy surface for both secretion and absorption, which the stomach performs as it processes food. The nuclei sit near the base, and the tissue often includes mucus-secreting goblet cells to protect and lubricate the lining. In contrast, simple squamous is a single layer of flat cells suited for rapid diffusion; simple cuboidal has cube-shaped cells good for secretion and absorption but not as tall; stratified squamous has multiple layers for protection in areas of wear. The described structure matches columnar epithelium.