Which condition is a form of arthritis that commonly affects the big toe, more common in men?

• A. Gout
• B. Osteoarthritis
• C. Rheumatoid arthritis
• D. Psoriatic arthritis

Answer: (A)

Gout is a form of inflammatory arthritis caused by uric acid crystal buildup in joints. It most commonly hits the big toe—the first toe joint—causing a sudden, extremely painful, red and swollen joint, often occurring at night. It’s more common in men, partly because men typically produce more uric acid and women’s uric acid levels rise after menopause. Risk factors include purine-rich foods, alcohol, obesity, and kidney function issues, all of which can raise uric acid and trigger attacks. Other conditions listed are different kinds of arthritis: osteoarthritis is a degenerative wear-and-tear condition usually seen in older people and various joints; rheumatoid arthritis is autoimmune and tends to affect multiple small joints symmetrically, more common in women; psoriatic arthritis is associated with psoriasis and can involve the toes but doesn’t present with the classic male-predominant big toe attack. Therefore, gout best fits the description.